背景：糖尿病是中国人群面临的最大的健康风险之一。而对老年人的危害更为显著。随着年龄的增长，糖尿病的并发症加剧，对老年人的身体机能产生重大影响，进而降低老年人的预期寿命。 目的：描述老年II型糖尿病及其并发症引起的机体功能丧失及衰弱状况。分析老年II型糖尿病患者虚弱状态的影响因素。 方法：对在华中科技大学同济医学院附属协和医院内分泌科住院的330例老年II型糖尿病患者(305例反馈良好)进行回顾性调查。我们使用了一般患者信息调查表，其中包括：与这项研究相关社会人口统计学数据，患者生活方式和临床数据。Fried虚弱量表被用来分析患者的虚弱状态。我们还应用了微量营养评估简表来评估患者的营养状况。应用charlson合并(CCI)来评估患者的合并症。 结果：患者的虚弱发生率为54.4％(166／305)，该组所占比例是三组中最高的。虚弱前期的发生率为21.6％(66／305)，而23.9％(73／305)的患者无虚弱发生。后两组患者比例均比虚弱组的患者比例低得多。主要的虚弱问题为肌无力，较少的运动量和缓慢的步行运动。在三组不同虚弱状态的糖尿病患者中，年龄、BMI、患者并发症的数量、MNA-SF评估指数、HB水平、ALB水平、HbA1c水平和CCI评分存在统计学差异(P<0.05)。Logistic回归分析表明：患者年龄、机体营养评分、糖化血红蛋白水平、CCI评分为老年II型糖尿病患者身体衰弱的影响因素。 结论：老年II型糖尿病患者的虚弱发生率较高。衰弱的发生与多种因素相关。提示医务工作者需对老年II型糖尿病患者提供更多的关注与帮助，来降低其发生衰弱的可能性及减慢其进展。 关键词：糖尿病，II型，老年患者，衰弱，影响因素，糖尿病管理。

 Background: Diabetes is one of the most significant risks to health in China among people of all ages. However, it poses an especially significant risk to the elderly. When the complications of diabetes are exacerbated by age-related decline, it can have a significant impact on the ability of the elderly people's body function. It can also reduce life expectancy. This study explores the connection between type II diabetes and loss of function and health status due to complications. Diabetes has its own set of health risks and complications, which become worse when glucose levels are not controlled. As the body age increasing, numerous factors can affect the ability of the body to recover from long-term physical, emotional, and social stressors. Aim: The aim of this study was to Analysis of debilitation status and affecting factors in elderly patients with type-II diabetes. Methods: A cross-sectional retrospective survey was performed on 330 elderly patients with type-II Diabetes Mellitus (305 patients with good feedback) who were hospitalized in the Endocrinology Department, Union Hospital of Huazhong University of Science and Technology, Tongji Medical College in Wuhan. We used general patient information questionnaires which include: social demographic data, living way, and clinical patients' data which were related to this research. Fried Frailty was administered to analyze the debilitation status of the participants. We also applied the Mini Nutritional Assessment Short-Form to assess the participants' nutritional status. Charlson Comorbidity Index was applied to assess the patients' comorbid conditions. Results: The debilitation rate among the patients was 54.4% (166/305), which was the highest group between the three groups. The pre-debilitation rate was 21.6% (66/305) and 23.9% (73/305) was showed to be without debilitation. Both of these two groups were much lower than the debilitation group. The main debilitation problems were muscle weakness, less physical activity, and slow walking motion. The diabetic patients of the three groups of debilitation status revealed a statistically significant difference in, age, BMI, number of diabetic patients' complications, MNA-SF assessment index, HB level, ALB level, HbAlc, and CCI score(P < 0.05). Logistic regression analysis showed that age, body nutrition score, HbAlc and CCI score were the influencing factors of debilitation in elderly patients with type II diabetes mellitus. Conclusion: Our study has shown that debilitation is highly incidence among elderly patients with type-II diabetes mellitus. And many factors are correlated with debilitation. Medical staff should pay great attention to the screening and evaluation of debilitating conditions in elderly patients with type-II diabetes. And to make directed interventions so as to decrease the occurrence of debilitation. KEYWORDS: elderly patients, age-related decline, debilitation, diabetes mellitus type-II, effect factors, diabetes management.